A resting cell sits in G0, outside the cycle
- The idea
- Predict
- See it
- Why
- Check
The idea
“A cell that isn't dividing is paused partway through the cycle, like in G2.”
The cycle is drawn as a loop, so it's easy to picture every cell on it. A cell waiting in G2 even sounds like it's resting.
The short version
The mistake: A cell that isn't dividing is paused partway through the cycle, like in G2.
What's actually true: A cell that stops dividing usually leaves the cycle from G1 and rests in G0, before its DNA is copied.
- Every phase after G1 is a step toward dividing.
- A cell that stops dividing usually leaves the cycle from G1, before S, and enters G0. It still does its job there, like making bile.
- Without growth factors, a cell usually doesn't pass the G1 checkpoint and moves into G0. It has no half-copied DNA to finish, so it can stay there for years.
On the exam: A cell that isn't dividing usually rests in G0, before its DNA is copied.