AP BiologyCommon mistakesNot every transport protein costs ATP

Not every transport protein costs ATP

  1. The idea
  2. Predict
  3. See it
  4. Why
  5. Check

The idea

“If a protein moves something across the membrane, the cell is spending ATP.”

A protein looks like a little machine, so it's easy to assume it runs on ATP. Many transport proteins are really just doors.

The short version

The mistake: If a protein moves something across the membrane, the cell is spending ATP.

What's actually true: Moving down a gradient through a channel or carrier costs no ATP. Moving against one, or in vesicles, takes energy.

  1. Molecules spread from more to less on their own. In facilitated diffusion, a channel or carrier gives polar or charged ones a path, and the gradient still does the work.
  2. Moving against a gradient takes energy. That's active transport, done by pumps like the sodium-potassium pump, which spends ATP.
  3. Vesicles cost energy too. Endocytosis and exocytosis use it to move large loads, whichever way the gradient runs.

On the exam: Ask which way the gradient runs. Down it is free, even through a protein. Up it takes energy, usually ATP.

Every common AP Biology mistake