AP BiologyCommon mistakesChannels are open pores, carriers change shape

Channels are open pores, carriers change shape

  1. The idea
  2. Predict
  3. See it
  4. Why
  5. Check

The idea

“A channel grabs each molecule and flips it across. A carrier is an open tunnel.”

Both proteins sit in the membrane and let solutes move down a gradient. It's easy to memorize that one changes shape and attach that fact to the wrong name.

The short version

The mistake: A channel grabs each molecule and flips it across. A carrier is an open tunnel.

What's actually true: A channel is an open pore that solutes pass straight through. A carrier binds each molecule and changes shape to move it.

  1. A channel has a water-filled pore. Ions or water pass straight through without the protein changing shape, so channels are fast.
  2. A gated channel changes shape to open or close, for example when a ligand binds. One opening lets many ions through.
  3. A carrier binds a molecule on one side, then changes shape to release it on the other. Each trip takes time, so carriers are slower and can saturate.

On the exam: A shape change for each molecule means a carrier. A pore the solute flows through means a channel.

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