AP BiologyCommon mistakesCrossing over or independent assortment?

Crossing over or independent assortment?

  1. The idea
  2. Predict
  3. See it
  4. Why
  5. Check

The idea

“Crossing over and independent assortment both shuffle alleles, so either can explain any new mix.”

Both happen in meiosis I and make new mixes of alleles, so they blur together. The difference is which genes each one can reach.

The short version

The mistake: Crossing over and independent assortment both shuffle alleles, so either can explain any new mix.

What's actually true: Independent assortment shuffles genes on different pairs. Only crossing over can split the alleles of genes on one chromosome.

  1. At metaphase I, each pair lines up either way, whatever the others do. So genes on two different pairs give four kinds of gametes equally.
  2. At anaphase I, homologs move whole, so lining up alone keeps genes on one chromosome together. Those genes are linked.
  3. In prophase I, a chromatid from each homolog trades matching segments. That makes new mixes of linked alleles. Genes farther apart recombine more often.

On the exam: Only crossing over splits genes on one chromosome. Independent assortment shuffles genes on different pairs.

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