AP BiologyCommon mistakesIn Aa × Aa, Aa is twice as likely as AA or aa

In Aa × Aa, Aa is twice as likely as AA or aa

  1. The idea
  2. Predict
  3. See it
  4. Why
  5. Check

The idea

“Two heterozygotes make AA, Aa and aa offspring, so each genotype is a third.”

Write out Aa × Aa and you find three genotypes, so a third each seems fair. Aa, though, can be built two different ways.

The short version

The mistake: Two heterozygotes make AA, Aa and aa offspring, so each genotype is a third.

What's actually true: In Aa × Aa, the heterozygote forms two ways, so the offspring are 1/4 AA, 1/2 Aa and 1/4 aa.

  1. Each Aa parent makes A and a gametes in equal numbers. Eggs and sperm meet at random, so the four Punnett boxes are equally likely.
  2. The three genotypes are not. Aa can form from an A egg and an a sperm, or from an a egg and an A sperm, so it fills two boxes.
  3. That gives AA, Aa and aa in a 1:2:1 ratio. With incomplete dominance or codominance, each genotype has its own phenotype, so phenotypes are 1:2:1 too.

On the exam: Count Punnett boxes, not genotype names. Aa fills two boxes, so it is twice as likely as AA or aa.

Every common AP Biology mistake