AP BiologyCommon mistakesMeiosis takes two divisions

Meiosis takes two divisions

  1. The idea
  2. Predict
  3. See it
  4. Why
  5. Check

The idea

“Meiosis I halves the chromosome number, so its two cells are the finished gametes.”

Meiosis I is the division that halves the chromosome number. Once 46 drops to 23, it's easy to think the cell is done.

The short version

The mistake: Meiosis I halves the chromosome number, so its two cells are the finished gametes.

What's actually true: Meiosis has two divisions. Meiosis I separates homologs, and meiosis II splits sister chromatids, making four cells.

  1. In S phase, before meiosis, the cell copies its DNA. Each chromosome then has two sister chromatids joined at the centromere.
  2. Meiosis I separates homologous chromosomes, the matching pair with one from each parent. The cells are haploid, but each chromosome still has two chromatids.
  3. Meiosis II then splits the sister chromatids, much like mitosis.

On the exam: Meiosis I halves the chromosome number. Meiosis II splits sister chromatids. A gamete needs both.

Every common AP Biology mistake